SCHEMBL29133018

SCHEMBL29133018

CC(C)(C)[Si](C)(C)CCOS(C)(=O)=O

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.46
TSHR P16473 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
MMP9 P14780 1/20 0.46
ALOX15 P16050 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29114468 0.78 CA2 (0.36)
SCHEMBL2058014 0.77 USP2 (0.55) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL4188554 0.72 USP2 (0.44) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL3595211 0.72 USP2 (0.55) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL2058172 0.71 USP2 (0.48) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL7548408 0.71 USP2 (0.48) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL10982965 0.69 KDM4E (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL10949282 0.69 KDM4E (0.58) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL26454809 0.69 KDM4E (0.52) USP2TSHRKDM4EALDH1A1LMNA
Ethane Dimethane Sulfonate SCHEMBL1336145 0.69 USP2 (0.75) USP2TSHRKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117304208-A Everolimus synthesis preparation method 福建省微生物研究所 2023-12-29 CN claimed
CN-117304208-A Everolimus synthesis preparation method 福建省微生物研究所 2023-12-29 CN disclosed
CN-116082363-A Alkyl synthesis method of rapamycin 40-hydroxy 西安交通大学 2023-05-09 CN disclosed