Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | HTR1D | P28221 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30622234 | 1.00 | MAPT (0.56) | MAPTRAB9AMAPK14NOTUMHTR1D | |
| SCHEMBL23850484 | 0.77 | RAB9A (0.65) | MAPTRAB9AMAPK14HTR1DSLC6A4 | |
| SCHEMBL31587612 | 0.77 | RAB9A (0.65) | MAPTRAB9AMAPK14HTR1DSLC6A4 | |
| SCHEMBL5113396 | 0.76 | RAB9A (0.45) | MAPTRAB9AMAPK14NOTUMSMN1; SMN2 | |
| SCHEMBL1199264 | 0.73 | NOTUM (0.46) | MAPTRAB9ANOTUMSMN1; SMN2GAA | |
| SCHEMBL4863208 | 0.72 | NPC1 (0.49) | MAPTRAB9AMAPK14NOTUMSMN1; SMN2 | |
| SCHEMBL4865403 | 0.72 | NPC1 (0.49) | MAPTRAB9AMAPK14NOTUMSMN1; SMN2 | |
| SCHEMBL8229627 | 0.72 | MAPT (0.47) | MAPTRAB9AMAPK14NOTUMHTR1D | |
| SCHEMBL31587825 | 0.72 | MAPT (1.00) | MAPTRAB9ASMN1; SMN2GAALMNA | |
| SCHEMBL23851060 | 0.72 | MAPT (1.00) | MAPTRAB9ASMN1; SMN2GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088884-A | Imidazopyridazine derivatives as GABAA receptor modulators, pharmaceutical compositions and uses | 上海赛默罗德生物科技有限公司 | 2023-11-21 | — | — | CN | disclosed |