Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1295880 | 0.94 | GPR119 (0.64) | GPR119FAAHSCN9A | |
| SCHEMBL3965373 | 0.93 | GPR119 (0.50) | GPR119SCN9A | |
| SCHEMBL7395646 | 0.92 | GPR119 (0.51) | GPR119SCN9A | |
| SCHEMBL3124615 | 0.92 | GPR119 (0.51) | GPR119SCN9A | |
| SCHEMBL345454 | 0.92 | GPR119 (0.51) | GPR119SCN9A | |
| SCHEMBL4002884 | 0.90 | GPR119 (0.65) | GPR119FAAHSCN9A | |
| SCHEMBL30759051 | 0.89 | GPR119 (0.51) | GPR119SCN9A | |
| SCHEMBL310750 | 0.85 | GPR119 (0.57) | GPR119SCN9A | |
| SCHEMBL30922520 | 0.85 | MEN1 (0.47) | GPR119SCN9A | |
| SCHEMBL1710891 | 0.85 | MEN1 (0.47) | GPR119SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285547-A | Macrocyclic compounds as modulators of CFTR, pharmaceutical compositions thereof, their use and methods of preparation | 弗特克斯药品有限公司 | 2023-12-26 | — | — | CN | disclosed |