Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3982504 | 0.95 | POLB (0.53) | POLBL3MBTL1GBA2LMNASMN1; SMN2 | |
| SCHEMBL6207733 | 0.95 | POLB (0.53) | POLBL3MBTL1GBA2LMNASMN1; SMN2 | |
| SCHEMBL1982237 | 0.95 | POLB (0.53) | POLBL3MBTL1GBA2LMNASMN1; SMN2 | |
| SCHEMBL10612338 | 0.94 | GBA2 (0.53) | POLBL3MBTL1GBA2LMNASMN1; SMN2 | |
| SCHEMBL2170278 | 0.89 | GBA2 (0.49) | POLBL3MBTL1GBA2LMNASMN1; SMN2 | |
| SCHEMBL7478389 | 0.89 | GBA2 (0.49) | POLBL3MBTL1GBA2LMNASMN1; SMN2 | |
| SCHEMBL7406503 | 0.89 | GBA2 (0.49) | POLBL3MBTL1GBA2LMNASMN1; SMN2 | |
| SCHEMBL6119301 | 0.89 | MAPT (0.43) | POLBGBA2LMNASMN1; SMN2MAPT | |
| SCHEMBL3036913 | 0.87 | LMNA (0.42) | POLBGBA2LMNASMN1; SMN2MAPT | |
| SCHEMBL6645335 | 0.86 | LMNA (0.41) | POLBL3MBTL1GBA2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |
| EP-3099300-A1 | ARYL LACTAM KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2016-12-07 | — | — | EP | disclosed |
| WO-2015116060-A1 | ARYL LACTAM KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-08-06 | — | — | WO | disclosed |
| CN-103102342-B | Aminoquinazoline derivative, salts thereof and application method | SUNSHINE LAKE PHARMA CO.,LTD. (CN) | 2014-10-29 | — | — | CN | disclosed |
| CN-103102342-A | Aminoquinazoline derivative, salts thereof and application method | GUANGDONG HEC PHARMACEUTICAL | 2013-05-15 | — | — | CN | disclosed |
| EP-1879884-B1 | AZOLE-BASED PHOSPHODIESTERASE INHIBITORS | RANBAXY LAB LTD (IN) | 2010-08-25 | — | — | EP | disclosed |
| EP-1879884-A1 | AZOLE-BASED PHOSPHODIESTERASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117653-A1 | AZOLE-BASED PHOSPHODIESTERASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |