Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.49 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.49 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13303940 | 0.83 | GAA (0.68) | GAAPKMGRIN2DGRIN3BGRIN1 | |
| SCHEMBL1824734 | 0.83 | GAA (0.54) | GAAPKMGRIN2DGRIN3BGRIN1 | |
| SCHEMBL13015140 | 0.81 | GAA (0.53) | GAAPKMGRIN2DGRIN3BGRIN1 | |
| SCHEMBL625509 | 0.80 | GAA (0.63) | GAAPKMGRIN2DGRIN3BGRIN1 | |
| SCHEMBL1826081 | 0.79 | PDE3B (0.62) | GAAPKMGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6910223 | 0.77 | GAA (0.59) | GAAPKMGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6768064 | 0.77 | GAA (0.59) | GAAPKMGRIN2DGRIN3BGRIN1 | |
| SCHEMBL28624153 | 0.77 | GAA (0.70) | GAAPKMGRIN2DGRIN3BGRIN1 | |
| SCHEMBL5393113 | 0.77 | GAA (0.59) | GAAPKMGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6768001 | 0.77 | GAA (0.65) | GAAPKMGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117327065-A | Carbazole derivatives as dopamine D2/3 receptor modulators | 北京大学 | 2024-01-02 | — | — | CN | disclosed |