Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | TSHR | P16473 | 2/20 | 0.77 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.58 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.58 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.58 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.52 |
| ▸ | ADH1B | P00325 | 1/20 | 0.52 |
| ▸ | ADH1C | P00326 | 1/20 | 0.52 |
| ▸ | ADH1A | P07327 | 1/20 | 0.52 |
| ▸ | ADH4 | P08319 | 1/20 | 0.52 |
| ▸ | ADH7 | P40394 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28919456 | 1.00 | ALDH1A1 (0.77) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| Alcohol SCHEMBL28919455 | 1.00 | ALDH1A1 (0.77) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| Ethylene Glycol SCHEMBL27527739 | 0.92 | ALDH1A1 (0.72) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| Propanol SCHEMBL28987488 | 0.92 | ALDH1A1 (0.72) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| SCHEMBL23929270 | 0.91 | TSHR (0.93) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| SCHEMBL23929261 | 0.91 | TSHR (0.93) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| SCHEMBL21611672 | 0.91 | TSHR (0.93) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| SCHEMBL23929276 | 0.91 | TSHR (0.93) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| SCHEMBL22535934 | 0.91 | TSHR (0.93) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| SCHEMBL20746342 | 0.91 | TSHR (0.93) | ALDH1A1TSHRS1PR2S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028989-B | Nylon composite powder, preparation method thereof and application thereof in laser sintering | 盱眙欧佰特粘土材料有限公司 | 2023-11-24 | — | — | CN | disclosed |