SCHEMBL29133533

SCHEMBL29133533

O=C(C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.60

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.60
CA2 P00918 10/20 0.35
CA1 P00915 9/20 0.35
MMP1 P03956 3/20 0.35
MMP2 P08253 3/20 0.35
MMP9 P14780 3/20 0.35
MMP8 P22894 3/20 0.35
MMP13 P45452 3/20 0.35
LMNA P02545 1/20 0.33
F2 P00734 2/20 0.31
PRSS1 P07477 2/20 0.31
PRSS2 P07478 2/20 0.31
PRSS3 P35030 2/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18937067 0.97 THRB (0.65) THRBCA2CA1MMP1MMP2
SCHEMBL20478151 0.97 THRB (0.65) THRBCA2CA1MMP1MMP2
SCHEMBL20478148 0.97 THRB (0.65) THRBCA2CA1MMP1MMP2
SCHEMBL28030131 0.97 THRB (0.65) THRBCA2CA1MMP1MMP2
SCHEMBL28417455 0.97 THRB (0.65) THRBCA2CA1MMP1MMP2
SCHEMBL18222576 0.94 THRB (0.55) THRBCA2CA1MMP1MMP2
SCHEMBL891907 0.90 THRB (0.48) THRBCA2CA1MMP1MMP2
SCHEMBL28005480 0.89 THRB (0.50) THRBCA2CA1MMP1MMP2
SCHEMBL2019285 0.88 THRB (0.55) THRBCA2CA1MMP1MMP2
SCHEMBL31091592 0.87 THRB (0.48) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024239911-A1 FOAMING COMPOSITION, AND POLYURETHANE FOAM AND PREPARATION METHOD THEREFOR 泉州宇极新材料科技有限公司 2024-11-28 WO claimed
CN-118325465-A Multi-scale crosslinked fluorosilicone-based ceramic repairing agent and preparation method thereof 海南核电有限公司 2024-07-12 CN claimed
WO-2024138976-A1 CATALYST SYSTEM AND PREPARATION METHOD THEREFOR AND USE THEREOF 上海华谊三爱富新材料有限公司 2024-07-04 WO claimed
CN-117343331-A Fluorosilicone resin for anticorrosive coating material and preparation method thereof 常州川羽新材料有限公司 2024-01-05 CN claimed
CN-117327449-A Friction-resistant self-drying fluorine-silicon coating material for fastener and preparation method thereof 常州川羽新材料有限公司 2024-01-02 CN claimed
CN-118325465-A Multi-scale crosslinked fluorosilicone-based ceramic repairing agent and preparation method thereof 海南核电有限公司 2024-07-12 CN disclosed
CN-117343331-A Fluorosilicone resin for anticorrosive coating material and preparation method thereof 常州川羽新材料有限公司 2024-01-05 CN disclosed
CN-117327449-A Friction-resistant self-drying fluorine-silicon coating material for fastener and preparation method thereof 常州川羽新材料有限公司 2024-01-02 CN disclosed