SCHEMBL29133891

SCHEMBL29133891

Cc1cc(C(c2ccccc2)(c2ccccc2)c2ccccc2)cc(C)c1N

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.54
CYP3A4 P08684 3/20 0.44
TDP1 Q9NUW8 3/20 0.44
ALDH1A1 P00352 2/20 0.44
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
KIF11 P52732 7/20 0.40
KCNN4 O15554 2/20 0.39
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
KCNH2 Q12809 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
BACE1 P56817 1/20 0.35
CD44 P16070 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22044783 1.00 POLB (0.54) POLBCYP3A4TDP1ALDH1A1TP53
SCHEMBL22050401 0.90 POLB (0.45) POLBCYP3A4TDP1ALDH1A1TP53
SCHEMBL22050362 0.83 KIF11 (0.48) POLBALDH1A1KIF11KCNN4ESR1
SCHEMBL22044364 0.80 ESR1 (0.55) POLBCYP3A4TDP1ALDH1A1TP53
SCHEMBL11023725 0.80 POLB (0.52) POLBCYP3A4TDP1ALDH1A1TP53
SCHEMBL22050361 0.79 FFAR4 (0.41) POLBCYP3A4TDP1ALDH1A1TP53
SCHEMBL22050404 0.78 CYP3A4 (0.46) CYP3A4TDP1ALDH1A1TP53TSHR
SCHEMBL4601584 0.77 PTGS1 (0.50) CYP3A4ALDH1A1ESR1ESR2CYP2C9
SCHEMBL24174896 0.76 GAA (0.42) TDP1ALDH1A1TSHRKIF11KCNN4
SCHEMBL11671062 0.76 ESR1 (0.50) CYP3A4ALDH1A1ESR1ESR2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117105990-B Catalyst for preparing polythiophene and P3HT material by catalysis 链行走新材料科技(广州)有限公司 2024-01-30 CN disclosed
CN-117105990-A Catalyst for preparing polythiophene and P3HT material by catalysis 链行走新材料科技(广州)有限公司 2023-11-24 CN disclosed