Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 20/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | STK16 | O75716 | 1/20 | 0.35 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.35 |
| ▸ | LATS1 | O95835 | 1/20 | 0.35 |
| ▸ | PAK4 | O96013 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | LYN | P07948 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | FER | P16591 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | ERCC2 | P18074 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12409784 | 0.82 | PTK2 (0.40) | PTK2AURKAJAK2STK16CDKL5 | |
| SCHEMBL29783098 | 0.82 | PTK2 (0.40) | PTK2AURKAJAK2STK16CDKL5 | |
| SCHEMBL29051675 | 0.82 | PTK2 (0.39) | PTK2AURKAJAK2STK16CDKL5 | |
| Hydrochloric Acid SCHEMBL29051685 | 0.81 | PTK2 (0.39) | PTK2AURKAJAK2STK16CDKL5 | |
| SCHEMBL14479713 | 0.79 | PTK2 (0.45) | PTK2AURKAJAK2STK16CDKL5 | |
| Acetic Acid SCHEMBL29853564 | 0.76 | PTK2 (0.39) | PTK2AURKAJAK2STK16CDKL5 | |
| Acetic Acid SCHEMBL1625936 | 0.76 | PTK2 (0.39) | PTK2AURKAJAK2STK16CDKL5 | |
| SCHEMBL11987607 | 0.76 | PTK2 (0.43) | PTK2AURKAJAK2STK16CDKL5 | |
| SCHEMBL16570123 | 0.75 | PTK2 (0.51) | PTK2PTK2B | |
| SCHEMBL30468433 | 0.72 | SRPK2 (0.45) | PTK2AURKAJAK2STK16CDKL5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043163-A | Pyrrolopyrimidine or pyrrolopyridine derivative and medical application thereof | 希格生科（深圳）有限公司 | 2023-11-10 | — | — | CN | disclosed |