SCHEMBL29134112

SCHEMBL29134112

ClC(Cl)c1ccccc1.ClCc1ccc(Cl)cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.50
CHRNA4 P43681 1/20 0.50
TSHR P16473 1/20 0.48
CYP1A2 P05177 2/20 0.47
CYP3A4 P08684 2/20 0.47
CYP2C9 P11712 2/20 0.47
CYP2C19 P33261 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
CYP2D6 P10635 1/20 0.47
EPHX1 P07099 1/20 0.47
SLC6A4 P31645 1/20 0.46
IDO1 P14902 4/20 0.44
SIGMAR1 Q99720 1/20 0.44
MAPK1 P28482 1/20 0.43
HDAC8 Q9BY41 2/20 0.42
TDO2 P48775 1/20 0.41
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
ALOX12 P18054 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,2-Dichlorobenzene SCHEMBL11813576 0.81 IDO1 (0.54) CHRNB2CHRNA4TSHRCYP1A2CYP3A4
SCHEMBL283639 0.81 IDO1 (0.62) CYP1A2CYP3A4CYP2C9CYP2C19IDO1
SCHEMBL4163742 0.79 IDO1 (0.60) CYP1A2CYP3A4CYP2C9CYP2C19IDO1
Hydrochloric Acid SCHEMBL10581269 0.79 IDO1 (0.60) CYP1A2CYP3A4CYP2C9CYP2C19IDO1
Methyl Alcohol SCHEMBL21223343 0.75 MAPK1 (0.59) TSHRCYP1A2CYP3A4CYP2C9CYP2C19
Trimethylammonium SCHEMBL11564446 0.74 IDO1 (0.54) CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6
SCHEMBL10972042 0.72 CHRNB2 (0.54) CHRNB2CHRNA4CYP1A2CYP3A4CYP2C9
SCHEMBL11853188 0.70 SLC6A4 (0.50) CHRNB2CHRNA4CYP1A2CYP3A4CYP2C9
SCHEMBL1539430 0.70 IDO1 (0.39) TSHRCYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL28353 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111312989-B Electrode for rechargeable lithium battery and rechargeable lithium battery comprising the same 三星SDI株式会社 2023-03-24 CN disclosed