Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 9/20 | 0.42 |
| ▸ | LPL | P06858 | 8/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30016964 | 1.00 | LIPG (0.42) | LIPGLPLROCK1HIF1AIRAK4 | |
| SCHEMBL1821378 | 0.83 | LIPG (0.47) | LIPGLPLROCK1HIF1AIRAK4 | |
| SCHEMBL27265290 | 0.81 | LIPG (0.44) | LIPGLPLHIF1AIRAK4 | |
| SCHEMBL27248072 | 0.81 | LIPG (0.44) | LIPGLPLROCK1HIF1AIRAK4 | |
| SCHEMBL26113775 | 0.81 | LIPG (0.44) | LIPGLPLHIF1AIRAK4 | |
| SCHEMBL23484493 | 0.79 | HIF1A (0.45) | LIPGLPLHIF1AIRAK4 | |
| SCHEMBL26476768 | 0.76 | LIPG (0.41) | LIPGLPLROCK1HIF1AIRAK4 | |
| SCHEMBL31312916 | 0.76 | LIPG (0.41) | LIPGLPLROCK1HIF1AIRAK4 | |
| SCHEMBL19471858 | 0.75 | LIPG (0.44) | LIPGLPLROCK1IRAK4 | |
| SCHEMBL16783747 | 0.74 | LIPG (0.47) | LIPGLPLIRAK4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120429-A | KHK inhibitor | 吉利德科学公司 | 2023-11-24 | — | — | CN | disclosed |