SCHEMBL29135048

SCHEMBL29135048

Clc1ccccc1-c1cccc(-c2cnc(-c3ccccc3)c(-c3ccccc3)n2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.46
SCN9A Q15858 1/20 0.45
ADORA2A P29274 4/20 0.43
ADORA1 P30542 4/20 0.43
ALOX5AP P20292 1/20 0.42
FEN1 P39748 1/20 0.42
TRPA1 O75762 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
ATM Q13315 1/20 0.40
CKS1B P61024 1/20 0.40
SKP1 P63208 1/20 0.40
SKP2 Q13309 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
ABL1 P00519 2/20 0.39
BACE1 P56817 1/20 0.38
GRM5 P41594 1/20 0.38
LMNA P02545 1/20 0.38
HPGD P15428 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29134679 0.88 CYP2A6 (0.53) CYP2A6SCN9AADORA2AADORA1ALOX5AP
SCHEMBL29134682 0.84 ADORA2A (0.50) CYP2A6ADORA2AADORA1ALOX5APFEN1
SCHEMBL30708988 0.82 ADORA1 (0.51) ADORA2AADORA1NPC1RAB9ACKS1B
SCHEMBL30708981 0.81 ADORA1 (0.54) ADORA2AADORA1NPC1RAB9ACKS1B
SCHEMBL29135049 0.81 ADORA1 (0.54) ADORA2AADORA1NPC1RAB9ACKS1B
SCHEMBL3521754 0.80 CNR1 (0.51) CYP2A6ADORA2AADORA1NPC1RAB9A
SCHEMBL29135051 0.77 CKS1B (0.42) ADORA2AADORA1CKS1BSKP1SKP2
SCHEMBL87574 0.77 CKS1B (0.55) NPC1RAB9ACKS1BSKP1SKP2
SCHEMBL30973837 0.77 ADORA2A (0.49) ADORA2AADORA1NPC1RAB9ACKS1B
SCHEMBL30708982 0.76 L3MBTL1 (0.53) ADORA2AADORA1NPC1RAB9ACKS1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117343102-A Compound, organic electroluminescent device and display device SK株式会社 2024-01-05 CN disclosed
CN-116903548-A Compound, composition for organic electroluminescent device, and display device SK株式会社 2023-10-20 CN disclosed