Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.74 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | STAT3 | P40763 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL29134718 | 0.91 | AKR1C3 (0.84) | AKR1C3AKR1C1GAAMEN1KMT2A | |
| SCHEMBL30679105 | 0.85 | AKR1C3 (1.00) | AKR1C3AKR1C1GAAMEN1KMT2A | |
| SCHEMBL664241 | 0.85 | AKR1C3 (1.00) | AKR1C3AKR1C1GAAMEN1KMT2A | |
| SCHEMBL29135079 | 0.84 | AKR1C3 (0.72) | AKR1C3AKR1C1GAAMEN1KMT2A | |
| SCHEMBL29134721 | 0.83 | AKR1C3 (0.70) | AKR1C3AKR1C1GAAMEN1KMT2A | |
| 2-Picolinic Acid SCHEMBL29135065 | 0.83 | AKR1C3 (0.70) | AKR1C3AKR1C1GAAMEN1KMT2A | |
| Thiophene Carboxylic Acid SCHEMBL29135074 | 0.83 | AKR1C3 (0.70) | AKR1C3AKR1C1GAAMEN1KMT2A | |
| SCHEMBL23559189 | 0.80 | KMT2A (0.81) | AKR1C3GAAMEN1KMT2ALMNA | |
| SCHEMBL663840 | 0.80 | AKR1C3 (1.00) | AKR1C3AKR1C1GAAMEN1KMT2A | |
| SCHEMBL30926847 | 0.78 | AKR1C3 (0.77) | AKR1C3AKR1C1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117298108-A | Androgen receptor and glucocorticoid receptor dual-target inhibitor and application thereof | 浙江师范大学 | 2023-12-29 | — | — | CN | disclosed |