Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 10/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29136068 | 0.87 | EGLN1 (0.53) | EGLN1YTHDC1 | |
| SCHEMBL30656517 | 0.87 | EGLN1 (0.53) | EGLN1YTHDC1 | |
| SCHEMBL29779107 | 0.87 | IDO1 (0.48) | EGLN1IDO1YTHDC1 | |
| SCHEMBL24617232 | 0.87 | IDO1 (0.48) | EGLN1IDO1YTHDC1 | |
| SCHEMBL29136019 | 0.83 | KMT2A (0.45) | EGLN1IDO1HTTKMT2APOLB | |
| SCHEMBL30656512 | 0.83 | KMT2A (0.45) | EGLN1IDO1HTTKMT2APOLB | |
| SCHEMBL2419097 | 0.76 | KMT2A (0.45) | EGLN1IDO1HTTKMT2APOLB | |
| SCHEMBL29136094 | 0.75 | ROCK1 (0.56) | — | |
| SCHEMBL29778921 | 0.75 | ROCK1 (0.56) | — | |
| SCHEMBL25427033 | 0.72 | EGLN1 (0.53) | EGLN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117136186-A | Selective inhibitors of ROCK1 and ROCK2 protein kinases and uses thereof | 盖诺斯克公司 | 2023-11-28 | — | — | CN | disclosed |