Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.50 |
| ▸ | PARP1 | P09874 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 2/20 | 0.49 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30679668 | 1.00 | USP30 (0.50) | USP30PARP1POLBKDM4EPIM1 | |
| SCHEMBL29862391 | 0.94 | USP30 (0.51) | USP30PARP1POLBKDM4EPIM1 | |
| SCHEMBL28833991 | 0.94 | USP30 (0.51) | USP30PARP1POLBKDM4EPIM1 | |
| SCHEMBL28833992 | 0.94 | USP30 (0.51) | USP30PARP1POLBKDM4EPIM1 | |
| SCHEMBL31358156 | 0.86 | USP30 (0.49) | USP30PARP1POLBPIM1PIM2 | |
| SCHEMBL30366200 | 0.84 | GAA (0.56) | POLBKDM4E | |
| SCHEMBL30089037 | 0.84 | GAA (0.56) | POLBKDM4E | |
| SCHEMBL30899633 | 0.84 | GAA (0.56) | POLBKDM4E | |
| SCHEMBL31358054 | 0.82 | USP30 (0.46) | USP30PARP1POLBPIM1PIM2 | |
| SCHEMBL4477690 | 0.82 | ROCK2 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117321042-A | Oxodihydro indole compounds for the treatment of inflammatory diseases or cancers | 豪夫迈·罗氏有限公司 | 2023-12-29 | — | — | CN | disclosed |