Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Dl-Phenylalanine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 2/20 | 0.45 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.45 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
| ▸ | PLAUR | Q03405 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylalanine SCHEMBL10428533 | 0.95 | ALPI (0.49) | ANPEPRNPEPDNPEPALPIPKM | |
| Dl-Phenylalanine SCHEMBL10428531 | 0.95 | ALPI (0.49) | ANPEPRNPEPDNPEPALPIPKM | |
| Phenylalanine SCHEMBL723829 | 0.87 | SLC7A5 (0.58) | ANPEPRNPEPDNPEPALPIPKM | |
| Dl-Phenylalanine SCHEMBL3691104 | 0.87 | SLC7A5 (0.58) | ANPEPRNPEPDNPEPALPIPKM | |
| Dl-Phenylalanine SCHEMBL29076351 | 0.86 | SLC7A5 (0.59) | ANPEPRNPEPDNPEPALPIPKM | |
| Dl-Phenylalanine SCHEMBL27692297 | 0.85 | THRB (0.44) | ANPEPRNPEPDNPEPALPIPKM | |
| Dl-Phenylalanine SCHEMBL28942429 | 0.84 | SLC7A5 (0.63) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Arginine SCHEMBL28196890 | 0.83 | NPY4R (0.46) | ANPEPRNPEPDNPEPALPIPKM | |
| Dl-Phenylalanine SCHEMBL28079151 | 0.83 | SLC7A5 (0.58) | ANPEPRNPEPDNPEPALPIPKM | |
| Dl-Phenylalanine SCHEMBL25221364 | 0.82 | SLC7A5 (0.65) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117110494-A | Application of beef quantitative target polypeptide in detection of beef content of meat product | 中国肉类食品综合研究中心 | 2023-11-24 | — | — | CN | disclosed |