SCHEMBL29136235

SCHEMBL29136235

CC(O)Cc1cccc(C(N)=O)c1C(N)=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 1/20 0.40
HTT P42858 1/20 0.39
PARP1 P09874 6/20 0.37
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
TSHR P16473 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CD38 P28907 2/20 0.35
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
METAP2 P50579 1/20 0.34
GAA P10253 1/20 0.34
POLB P06746 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29136234 0.90 IRAK4 (0.38) IRAK4HTTPARP1KEAP1NFE2L2
SCHEMBL8508451 0.84 IRAK4 (0.47) IRAK4HTTPARP1KEAP1NFE2L2
SCHEMBL3377091 0.84 IRAK4 (0.47) IRAK4HTTPARP1KEAP1NFE2L2
SCHEMBL8507009 0.84 IRAK4 (0.47) IRAK4HTTPARP1KEAP1NFE2L2
SCHEMBL5935461 0.83 IRAK4 (0.40) IRAK4HTTPARP1KEAP1NFE2L2
SCHEMBL30776574 0.83 IRAK4 (0.40) IRAK4HTTPARP1KEAP1NFE2L2
SCHEMBL6566956 0.80 PARP1 (0.47) IRAK4HTTPARP1KEAP1NFE2L2
SCHEMBL17961587 0.78 FOLH1 (0.43) HTTKMT2AMEN1KDM4EALDH1A1
SCHEMBL2129165 0.77 PARP1 (0.46) PARP1KEAP1NFE2L2KMT2AMEN1
SCHEMBL1063004 0.76 BID (0.41) HTTPARP1KMT2AMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117003980-A Polyol composition, polyurethane hard foam and preparation method thereof 红宝丽集团股份有限公司 2023-11-07 CN disclosed