Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 8/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2911858 | 0.87 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL2912573 | 0.85 | MAPT (0.59) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL28033776 | 0.84 | KMT2A (0.56) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL642934 | 0.82 | MAPT (0.59) | MAPTLMNAMEN1MAPK1KMT2A | |
| SCHEMBL29204581 | 0.82 | PDE4B (0.52) | PDE4APDE4BPDE4CPDE4DL3MBTL1 | |
| SCHEMBL12035935 | 0.81 | TTR (0.54) | MAPTGAAMEN1KMT2AKDM4E | |
| SCHEMBL3738587 | 0.81 | MAPT (0.64) | L3MBTL1MAPTPOLBGAALMNA | |
| SCHEMBL19558318 | 0.80 | CA12 (0.54) | MAPTPOLBLMNAMEN1MAPK1 | |
| SCHEMBL3009040 | 0.79 | MAPT (0.43) | MAPTGAALMNAMEN1KMT2A | |
| SCHEMBL3629768 | 0.79 | NOTUM (0.48) | L3MBTL1MAPTLMNAMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879884-B1 | AZOLE-BASED PHOSPHODIESTERASE INHIBITORS | RANBAXY LAB LTD (IN) | 2010-08-25 | — | — | EP | disclosed |
| EP-1879884-A1 | AZOLE-BASED PHOSPHODIESTERASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117653-A1 | AZOLE-BASED PHOSPHODIESTERASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |