Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.50 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.50 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.50 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.50 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL642934 | 0.94 | MAPT (0.59) | MAPTTSHRKMT2AALDH1A1HSD17B10 | |
| SCHEMBL2912393 | 0.87 | CA12 (0.65) | TSHRKMT2AALDH1A1HDAC3TUBB4A | |
| SCHEMBL19558318 | 0.85 | CA12 (0.54) | MAPTTSHRKMT2AALDH1A1HSD17B10 | |
| SCHEMBL2913639 | 0.85 | PDE4A (0.47) | MAPTKMT2APDE4APDE4BPDE4C | |
| SCHEMBL3629768 | 0.84 | NOTUM (0.48) | MAPTTSHRKMT2AALDH1A1HSD17B10 | |
| SCHEMBL3009040 | 0.84 | MAPT (0.43) | MAPTTSHRKMT2AALDH1A1HSD17B10 | |
| SCHEMBL1018163 | 0.84 | NOTUM (0.44) | MAPTTSHRKMT2AALDH1A1HSD17B10 | |
| SCHEMBL18581520 | 0.84 | USP2 (0.56) | MAPTALDH1A1HSD17B10PDE4APDE4B | |
| SCHEMBL12035935 | 0.84 | TTR (0.54) | MAPTTSHRKMT2AALDH1A1HSD17B10 | |
| SCHEMBL3023191 | 0.84 | MGLL (0.49) | MAPTTSHRKMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879884-B1 | AZOLE-BASED PHOSPHODIESTERASE INHIBITORS | RANBAXY LAB LTD (IN) | 2010-08-25 | — | — | EP | disclosed |
| EP-1879884-A1 | AZOLE-BASED PHOSPHODIESTERASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117653-A1 | AZOLE-BASED PHOSPHODIESTERASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |
| US-6121274-A | PHOSPHODIESTERASE INHIBITOR FOR TREATMENT OF RESPIRATORY SYSTEM DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-09-19 | — | — | US | disclosed |