Methane

Methane

SCHEMBL29136471

C.Oc1cc2ccccc2o1

nearest known ligand 0.55

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.55
TYR P14679 1/20 0.55
DAO P14920 1/20 0.55
AKR1B1 P15121 1/20 0.55
KDM4E B2RXH2 2/20 0.52
FLT3 P36888 1/20 0.52
MGLL Q99685 1/20 0.52
HSD17B10 Q99714 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
ALOX5 P09917 1/20 0.48
CYP2A6 P11509 2/20 0.47
LOXL2 Q9Y4K0 1/20 0.47
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
GAPDH P04406 2/20 0.46
ALDH1A1 P00352 1/20 0.46
ESR1 P03372 1/20 0.46
GAA P10253 1/20 0.46
ESR2 Q92731 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL276910 0.98 HPGD (0.57) HPGDTYRDAOAKR1B1KDM4E
SCHEMBL27489198 0.98 HPGD (0.57) HPGDTYRDAOAKR1B1KDM4E
Water SCHEMBL28199096 0.95 HPGD (0.55) HPGDTYRDAOAKR1B1KDM4E
Urea SCHEMBL27701713 0.87 FLT3 (0.60) HPGDTYRDAOAKR1B1KDM4E
Propene SCHEMBL28102085 0.86 HPGD (0.47) HPGDTYRDAOAKR1B1KDM4E
Acetic Acid SCHEMBL15971810 0.86 KDM4E (0.54) HPGDTYRDAOAKR1B1KDM4E
Carbamic Acid SCHEMBL27939305 0.86 FLT3 (0.58) HPGDTYRDAOAKR1B1FLT3
Urea SCHEMBL27459733 0.84 FLT3 (0.56) HPGDTYRDAOAKR1B1KDM4E
SCHEMBL27994219 0.84 HPGD (0.46) HPGDTYRDAOAKR1B1KDM4E
Benzofuran SCHEMBL27593889 0.84 HPGD (0.46) HPGDTYRDAOAKR1B1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362162-A Preparation method of carbonyl compound 中国科学院大连化学物理研究所 2024-01-09 CN disclosed