SCHEMBL276910

SCHEMBL276910

Oc1cc2ccccc2o1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.57
TYR P14679 1/20 0.57
DAO P14920 1/20 0.57
AKR1B1 P15121 1/20 0.57
KDM4E B2RXH2 3/20 0.54
FLT3 P36888 1/20 0.54
MGLL Q99685 1/20 0.54
HSD17B10 Q99714 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
ALOX5 P09917 1/20 0.50
CYP2A6 P11509 2/20 0.48
LOXL2 Q9Y4K0 1/20 0.48
RAB9A P51151 3/20 0.47
NPC1 O15118 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
GAPDH P04406 2/20 0.47
ALDH1A1 P00352 2/20 0.47
ESR1 P03372 1/20 0.47
GAA P10253 1/20 0.47
ESR2 Q92731 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27489198 1.00 HPGD (0.57) HPGDTYRDAOAKR1B1KDM4E
Methane SCHEMBL29136471 0.98 HPGD (0.55) HPGDTYRDAOAKR1B1KDM4E
Water SCHEMBL28199096 0.98 HPGD (0.55) HPGDTYRDAOAKR1B1KDM4E
Urea SCHEMBL27701713 0.89 FLT3 (0.60) HPGDTYRDAOAKR1B1KDM4E
Acetic Acid SCHEMBL15971810 0.88 KDM4E (0.54) HPGDTYRDAOAKR1B1KDM4E
Carbamic Acid SCHEMBL27939305 0.88 FLT3 (0.58) HPGDTYRDAOAKR1B1FLT3
Propene SCHEMBL28102085 0.88 HPGD (0.47) HPGDTYRDAOAKR1B1KDM4E
SCHEMBL27994219 0.86 HPGD (0.46) HPGDTYRDAOAKR1B1KDM4E
Benzofuran SCHEMBL27593889 0.86 HPGD (0.46) HPGDTYRDAOAKR1B1KDM4E
Urea SCHEMBL27459733 0.86 FLT3 (0.56) HPGDTYRDAOAKR1B1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119775241-A 5-Hydroxy benzofuran derivative and preparation method thereof 华东理工大学 2025-04-08 CN claimed
CN-117126338-A Modified coumarone resin-polystyrene emulsion and preparation method thereof 宝武碳业科技股份有限公司 2023-11-28 CN claimed
CN-117126421-A Production method of hydroxyl coumarone resin emulsion 宝武碳业科技股份有限公司 2023-11-28 CN claimed
CN-109549918-B Ophthalmic medicine composition, ophthalmic medicine box and medical application thereof 沈阳兴齐眼药股份有限公司 2023-05-23 CN claimed
CN-114853699-A Synthetic method of benfuriol 盐城师范学院 2022-08-05 CN claimed
CN-111436187-A Blend of a bio-stimulant based on folate impurity 10 and an agrochemical of interest that produces a quantitative, qualitative and time-related result enhancement as observed in crops of plants of interest UPL有限责任公司 2020-07-21 CN claimed
US-20190221750-A1 CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED CYCLIC COMPOUND SAMSUNG ELECTRONICS CO., LTD. (KR) 2019-07-18 US claimed
CN-109851601-A A kind of preparation method and use of cyano-containing benzofuran 吉首大学 2019-06-07 CN claimed
CN-108690008-A A kind of 1,3,4- oxadiazole class compounds containing benzofuranyl 湖南博隽生物医药有限公司 2018-10-23 CN claimed
CN-108366597-A Mixture of substances 西姆莱斯有限公司 2018-08-03 CN claimed
EP-0648488-A1 Method to alter hairgrowth and compositions therefor L'OREAL (FR) 1995-04-19 EP claimed
US-5203875-A Hair dyes also using ortho- and para-phenylenediamines or aminophenols; colorfastness; washfastness; perspiration resistance L'OREAL (FR) 1993-04-20 US claimed
EP-0420570-A2 Trans 2,3-disubstituted-2,3-dihydro-5-hydroxy-benzofurans as inhibitors of leukotriene biosynthesis MERCK & CO. INC. (US) 1991-04-03 EP claimed
EP-0203954-B1 BENZOFURAN DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PESTICIDES CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) 1989-09-06 EP claimed
US-4851587-A Single solvent process for preparing 2-methallyloxy-phenol from catechol FMC CORPORATION (US) 1989-07-25 US claimed
EP-0200187-B1 PROCESS FOR THE PREPARATION OF 2-HYDROXY-DIBENZOFURAN-3-CARBOXYLIC ACID OR ITS ALKALI SALTS HOECHST AKTIENGESELLSCHAFT (DE) 1989-06-07 EP claimed
EP-0203954-A1 Benzofuran derivatives, their preparation and their use as pesticides. CHINOIN GYOGYSZER ES VEGYESZET (HU) 1986-12-10 EP claimed
EP-0200187-A2 Process for the preparation of 2-hydroxy-dibenzofuran-3-carboxylic acid or its alkali salts HOECHST AKTIENGESELLSCHAFT (DE) 1986-11-05 EP claimed
WO-1986003202-A1 NEW PESTICIDES Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) 1986-06-05 WO claimed
EP-0071487-A2 Improved process for the preparation of carbofuran and novel intermediate UNION CARBIDE CORPORATION (US) 1983-02-09 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190221750-A1 CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE CONDENSED CYCLIC COMPOUND CRY1, CRY2, MCM4 HPGD 2153/4885TYR 2553/4885DAO 4446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.