Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.40 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL29191531 | 1.00 | FDPS (0.44) | FDPSOPRM1DNM1SPHK1LMNA | |
| Bromide SCHEMBL2348951 | 1.00 | FDPS (0.44) | FDPSOPRM1DNM1SPHK1LMNA | |
| SCHEMBL13058111 | 0.98 | FDPS (0.45) | FDPSOPRM1DNM1SPHK1LMNA | |
| SCHEMBL16908418 | 0.98 | FDPS (0.45) | FDPSOPRM1DNM1SPHK1LMNA | |
| SCHEMBL9051998 | 0.98 | FDPS (0.45) | FDPSOPRM1DNM1SPHK1LMNA | |
| SCHEMBL16109187 | 0.98 | FDPS (0.45) | FDPSOPRM1DNM1SPHK1LMNA | |
| SCHEMBL9635328 | 0.98 | FDPS (0.45) | FDPSOPRM1DNM1SPHK1LMNA | |
| SCHEMBL6351247 | 0.98 | FDPS (0.45) | FDPSOPRM1DNM1SPHK1LMNA | |
| Hydrochloric Acid SCHEMBL6890712 | 0.95 | FDPS (0.44) | FDPSOPRM1DNM1SPHK1LMNA | |
| Hydrochloric Acid SCHEMBL6890298 | 0.95 | FDPS (0.44) | FDPSOPRM1DNM1SPHK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117363125-A | Water-based paint and preparation process thereof | 广州福诚美化工有限公司 | 2024-01-09 | — | — | CN | claimed |
| CN-117362837-A | Functional MPP cable tube and production method thereof | 杭州佳磊环保科技有限公司 | 2024-01-09 | — | — | CN | disclosed |