SCHEMBL29136571

SCHEMBL29136571

NNC(=O)NNC(=O)c1ccccn1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 7/20 0.59
KDM4E B2RXH2 7/20 0.59
HTT P42858 5/20 0.59
ALDH1A1 P00352 1/20 0.59
SMN1; SMN2 Q16637 4/20 0.56
LMNA P02545 3/20 0.56
OPRK1 P41145 2/20 0.56
TDP1 Q9NUW8 1/20 0.56
RAB9A P51151 2/20 0.54
MAPT P10636 2/20 0.54
NPC1 O15118 1/20 0.54
PKM P14618 1/20 0.54
HPGD P15428 1/20 0.54
CDK5 Q00535 1/20 0.54
PAX8 Q06710 1/20 0.54
CDK5R1 Q15078 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
HDAC3 O15379 1/20 0.53
HDAC4 P56524 1/20 0.53
HDAC1 Q13547 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1147702 0.87 KDM4E (0.73) TLR7KDM4EHTTALDH1A1SMN1; SMN2
SCHEMBL28131851 0.83 HDAC3 (0.61) TLR7KDM4EHTTALDH1A1SMN1; SMN2
SCHEMBL109657 0.83 HDAC3 (0.61) TLR7KDM4EHTTALDH1A1SMN1; SMN2
Bromide SCHEMBL27617389 0.82 HDAC3 (0.59) TLR7KDM4EHTTALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL17500942 0.82 HDAC3 (0.59) TLR7KDM4EHTTALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL8939068 0.82 HDAC3 (0.59) TLR7KDM4EHTTALDH1A1SMN1; SMN2
Methylene Chloride SCHEMBL28230710 0.80 HDAC3 (0.57) TLR7KDM4EHTTALDH1A1SMN1; SMN2
SCHEMBL14810907 0.80 KDM4E (0.67) TLR7KDM4EHTTALDH1A1SMN1; SMN2
Azapicyl SCHEMBL24931095 0.79 KDM4E (0.68) TLR7KDM4EHTTALDH1A1SMN1; SMN2
SCHEMBL24931101 0.79 TLR7 (0.78) TLR7KDM4EHTTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362224-A Water-soluble carbohydrazide derivative, preparation method thereof and method for detecting ions or amino acids 内蒙古工业大学 2024-01-09 CN disclosed