Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947676 | 1.00 | HDAC1 (0.48) | HDAC1MEN1KMT2ANPC1GAA | |
| SCHEMBL29947681 | 0.91 | AURKA (0.53) | HDAC1MEN1KMT2ANPC1GAA | |
| SCHEMBL29136655 | 0.91 | AURKA (0.53) | HDAC1MEN1KMT2ANPC1GAA | |
| SCHEMBL12757192 | 0.88 | MEN1 (0.48) | HDAC1MEN1KMT2ANPC1GAA | |
| SCHEMBL1232910 | 0.87 | BCHE (0.52) | MEN1KMT2ANPC1GAARAB9A | |
| SCHEMBL204017 | 0.85 | MEN1 (0.48) | HDAC1MEN1KMT2ANPC1GAA | |
| SCHEMBL29475728 | 0.85 | BRD4 (0.47) | MEN1KMT2ANPC1GAARAB9A | |
| SCHEMBL1034070 | 0.85 | BRD4 (0.47) | MEN1KMT2ANPC1GAARAB9A | |
| SCHEMBL1232778 | 0.85 | STK17B (0.47) | MEN1KMT2ANPC1GAARAB9A | |
| SCHEMBL30503514 | 0.85 | BRD4 (0.47) | MEN1KMT2ANPC1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355341-A | TLR7 and TLR8 agonists for the treatment of cancer and/or infectious diseases | 纽约州立大学研究基金会 | 2024-01-05 | — | — | CN | disclosed |