SCHEMBL1034070

SCHEMBL1034070

CC(C)(C)OC(=O)NCCCCNc1c(N)cnc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 3/20 0.47
CA12 O43570 4/20 0.46
CA1 P00915 4/20 0.46
CA2 P00918 4/20 0.46
CA9 Q16790 4/20 0.46
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
GAA P10253 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
BCHE P06276 1/20 0.45
STK17B O94768 1/20 0.45
STK17A Q9UEE5 1/20 0.45
CYP3A4 P08684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29475728 1.00 BRD4 (0.47) BRD4CA12CA1CA2CA9
SCHEMBL30503514 1.00 BRD4 (0.47) BRD4CA12CA1CA2CA9
Hydrochloric Acid SCHEMBL8140313 0.99 BRD4 (0.46) BRD4CA12CA1CA2CA9
SCHEMBL1232778 0.98 STK17B (0.47) BRD4CA12CA1CA2CA9
SCHEMBL1232910 0.93 BCHE (0.52) BRD4CA12CA1CA2CA9
SCHEMBL1039304 0.89 MEN1 (0.44) CA12CA1CA2CA9MEN1
SCHEMBL12757192 0.88 MEN1 (0.48) BRD4MEN1NPC1GAARAB9A
SCHEMBL3352911 0.85 KDM4E (0.46) BRD4CA12CA1CA2CA9
SCHEMBL204017 0.85 MEN1 (0.48) MEN1NPC1GAARAB9AKMT2A
SCHEMBL29136642 0.85 HDAC1 (0.48) BRD4CA1CA2MEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12569566-B2 Compositions containing, methods and uses of antibody-TLR agonist conjugates AMBRX, INC. (US) 2026-03-10 US disclosed
US-20230372511-A1 ANTIBODY-IMMUNE AGONIST CONJUGATE AND APPLICATIONS THEREOF GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) 2023-11-23 US disclosed
US-20230372511-A1 ANTIBODY-IMMUNE AGONIST CONJUGATE AND APPLICATIONS THEREOF GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) 2023-11-23 US disclosed
US-20230302150-A1 ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF AMBRX, INC. (US) 2023-09-28 US disclosed
US-20230302150-A1 ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF AMBRX, INC. (US) 2023-09-28 US disclosed
US-20230302150-A1 ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF AMBRX, INC. (US) 2023-09-28 US disclosed
US-11717576-B2 Antibody-immune agonist conjugate and applications thereof GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) 2023-08-08 US disclosed
US-11717576-B2 Antibody-immune agonist conjugate and applications thereof GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) 2023-08-08 US disclosed
CN-116457023-A antibody-TLR agonist conjugates, methods and uses thereof AMBRX公司 2023-07-18 CN disclosed
EP-4199968-A1 ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF Ambrx, Inc. (US) 2023-06-28 EP disclosed
EP-1198233-A4 SULFONAMIDE AND SULFAMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES CO (US) 2002-07-24 EP disclosed
EP-1198233-A1 SULFONAMIDE AND SULFAMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M Innovative Properties Company (US) 2002-04-24 EP disclosed
EP-1198232-A1 UREA SUBSTITUTED IMIDAZOQUINOLINES 3M Innovative Properties Company (US) 2002-04-24 EP disclosed
US-6376669-B1 COMPLEXES 3M INNOVATIVE PROPERTIES COMPANY 2002-04-23 US disclosed
US-6331539-B1 INDUCE BIOSYNTHESIS OF INTERFERON ALPHA IN ANIMALS 3M INNOVATIVE PROPERTIES COMPANY 2001-12-18 US disclosed
WO-2001034709-A1 DYE LABELED IMIDAZOQUINOLINE COMPOUNDS 3M INNOVATIVE PROPERTIES COMPANY (US) 2001-05-17 WO disclosed
WO-2000076518-A1 UREA SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-12-21 WO disclosed
WO-2000076519-A1 SULFONAMIDE AND SULFAMIDE SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-12-21 WO disclosed
US-6069149-A ANTIALLERGENS, ANTIINFLAMMATORY AGENTS TERUMO KABUSHIKI KAISHA (JP) 2000-05-30 US disclosed
EP-0894797-A1 NOVEL AMIDE DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF TERUMO KABUSHIKI KAISHA (JP) 1999-02-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230372511-A1 ANTIBODY-IMMUNE AGONIST CONJUGATE AND APPLICATIONS THEREOF FCGR1A, FCGR2A, TLR3 BRD4 3529/4885CA12 932/4885CA1 2530/4885
US-20230302150-A1 ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF TLR3, TLR1, TLR9 BRD4 1406/4885CA12 3178/4885CA1 4735/4885
US-11717576-B2 Antibody-immune agonist conjugate and applications thereof FCGR1A, FCGR2A, TLR3 BRD4 3529/4885CA12 932/4885CA1 2530/4885
US-12569566-B2 Compositions containing, methods and uses of antibody-TLR agonist conjugates TLR3, TLR2, TLR1 BRD4 1079/4885CA12 2287/4885CA1 3426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.