Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24738194 | 1.00 | KMT2A (0.35) | KMT2ATP53SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL24739001 | 0.88 | KMT2A (0.35) | KMT2ATP53SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL29302545 | 0.81 | MMP1 (0.34) | KMT2ATP53SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL29302685 | 0.80 | TP53 (0.33) | KMT2ATP53SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL24739910 | 0.79 | TP53 (0.33) | KMT2ATP53SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL24738998 | 0.79 | TP53 (0.31) | TP53SMN1; SMN2 | |
| SCHEMBL24737437 | 0.79 | CA1 (0.42) | HSD17B10SUV39H2ALDH1A1IGF1R | |
| SCHEMBL24737491 | 0.79 | PPARA (0.31) | — | |
| SCHEMBL29304600 | 0.78 | — | — | |
| SCHEMBL29879311 | 0.76 | AAK1 (0.30) | TP53SMN1; SMN2AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355521-A | Heteroaryl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | disclosed |