Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 8/20 | 0.41 |
| ▸ | TYK2 | P29597 | 5/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24739072 | 1.00 | DGAT1 (0.42) | DGAT1KLKB1TYK2METTL3BRAF | |
| SCHEMBL29136754 | 1.00 | DGAT1 (0.42) | DGAT1KLKB1TYK2METTL3BRAF | |
| SCHEMBL27957767 | 1.00 | DGAT1 (0.42) | DGAT1KLKB1TYK2METTL3BRAF | |
| SCHEMBL29879153 | 1.00 | DGAT1 (0.42) | DGAT1KLKB1TYK2METTL3BRAF | |
| SCHEMBL29136756 | 1.00 | DGAT1 (0.42) | DGAT1KLKB1TYK2METTL3BRAF | |
| SCHEMBL24737798 | 0.92 | TYK2 (0.42) | TYK2BRAF | |
| SCHEMBL29137018 | 0.92 | TYK2 (0.42) | TYK2BRAF | |
| SCHEMBL29137019 | 0.92 | TYK2 (0.42) | TYK2BRAF | |
| SCHEMBL24738308 | 0.91 | KLKB1 (0.39) | KLKB1TYK2METTL3 | |
| SCHEMBL29879563 | 0.91 | KLKB1 (0.39) | KLKB1TYK2METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355521-A | Heteroaryl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | disclosed |