Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 11/20 | 0.41 |
| ▸ | TRPM5 | Q9NZQ8 | 2/20 | 0.37 |
| ▸ | BRAF | P15056 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24737628 | 1.00 | TYK2 (0.41) | TYK2TRPM5BRAF | |
| SCHEMBL29136961 | 1.00 | TYK2 (0.41) | TYK2TRPM5BRAF | |
| SCHEMBL29137019 | 0.91 | TYK2 (0.42) | TYK2TRPM5BRAF | |
| SCHEMBL24737798 | 0.91 | TYK2 (0.42) | TYK2TRPM5BRAF | |
| SCHEMBL29137018 | 0.91 | TYK2 (0.42) | TYK2TRPM5BRAF | |
| SCHEMBL29136885 | 0.89 | LRRK2 (0.39) | TRPM5 | |
| SCHEMBL24738275 | 0.89 | LRRK2 (0.39) | TRPM5 | |
| SCHEMBL29136884 | 0.89 | LRRK2 (0.39) | TRPM5 | |
| SCHEMBL24739072 | 0.88 | DGAT1 (0.42) | TYK2BRAF | |
| SCHEMBL29136754 | 0.88 | DGAT1 (0.42) | TYK2BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355521-A | Heteroaryl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | disclosed |