Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29302520 | 1.00 | SLC9A1 (0.64) | SLC9A1LMNAALDH1A1MEN1MAPT | |
| SCHEMBL3040710 | 1.00 | SLC9A1 (0.64) | SLC9A1LMNAALDH1A1MEN1MAPT | |
| SCHEMBL21501073 | 1.00 | SLC9A1 (0.64) | SLC9A1LMNAALDH1A1MEN1MAPT | |
| SCHEMBL29136850 | 1.00 | SLC9A1 (0.64) | SLC9A1LMNAALDH1A1MEN1MAPT | |
| SCHEMBL31684359 | 1.00 | SLC9A1 (0.64) | SLC9A1LMNAALDH1A1MEN1MAPT | |
| SCHEMBL24737484 | 1.00 | SLC9A1 (0.64) | SLC9A1LMNAALDH1A1MEN1MAPT | |
| SCHEMBL7000518 | 1.00 | SLC9A1 (0.64) | SLC9A1LMNAALDH1A1MEN1MAPT | |
| SCHEMBL29830097 | 0.88 | SLC9A1 (0.66) | SLC9A1LMNAALDH1A1MEN1MAPT | |
| SCHEMBL29136847 | 0.88 | SLC9A1 (0.66) | SLC9A1LMNAALDH1A1MEN1MAPT | |
| SCHEMBL29136846 | 0.88 | SLC9A1 (0.66) | SLC9A1LMNAALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355523-A | Polycyclic inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | disclosed |
| CN-117355521-A | Heteroaryl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | disclosed |