Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.58 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24738883 | 1.00 | TTR (0.58) | TTRAPPPTPN1FDPSCA12 | |
| SCHEMBL29879436 | 1.00 | TTR (0.58) | TTRAPPPTPN1FDPSCA12 | |
| SCHEMBL15911970 | 0.84 | TTR (0.57) | TTRAPPPTPN1FDPSCA12 | |
| SCHEMBL28287607 | 0.83 | TTR (0.55) | TTRAPPPTPN1FDPSCA12 | |
| SCHEMBL25075381 | 0.82 | IAPP (0.54) | TTRAPPPTPN1FDPSCA12 | |
| SCHEMBL26820204 | 0.82 | IAPP (0.54) | TTRAPPPTPN1FDPSCA12 | |
| SCHEMBL18639965 | 0.81 | TTR (0.54) | TTRAPPPTPN1FDPSCA12 | |
| SCHEMBL20738228 | 0.81 | TTR (0.54) | TTRAPPPTPN1FDPSCA12 | |
| SCHEMBL18639968 | 0.81 | TTR (0.54) | TTRAPPPTPN1FDPSCA12 | |
| SCHEMBL9106504 | 0.81 | TTR (0.54) | TTRAPPPTPN1FDPSCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355521-A | Heteroaryl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | disclosed |