Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 17/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21355420 | 0.84 | METTL3 (0.48) | METTL3KLKB1 | |
| SCHEMBL21355335 | 0.80 | KDM4E (0.51) | METTL3KLKB1 | |
| SCHEMBL29141754 | 0.80 | METTL3 (0.41) | METTL3KLKB1 | |
| SCHEMBL21355035 | 0.79 | METTL3 (0.47) | METTL3KLKB1 | |
| SCHEMBL21368346 | 0.79 | METTL3 (0.45) | METTL3KLKB1 | |
| SCHEMBL21354790 | 0.79 | METTL3 (0.45) | METTL3KLKB1 | |
| SCHEMBL21355379 | 0.78 | METTL3 (0.43) | METTL3KLKB1 | |
| SCHEMBL29958525 | 0.78 | METTL3 (0.41) | METTL3KLKB1 | |
| SCHEMBL27033584 | 0.78 | METTL3 (0.41) | METTL3KLKB1 | |
| SCHEMBL21355039 | 0.78 | METTL3 (0.48) | METTL3KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355521-A | Heteroaryl inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | disclosed |
| CN-117355523-A | Polycyclic inhibitors of plasma kallikrein | 武田药品工业株式会社 | 2024-01-05 | — | — | CN | disclosed |