Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1199962 | 0.85 | CES1 (0.50) | HPGDERCC5FEN1HTTALDH1A1 | |
| SCHEMBL29645048 | 0.85 | CES1 (0.50) | HPGDERCC5FEN1HTTALDH1A1 | |
| Ethane SCHEMBL20186012 | 0.83 | CES1 (0.48) | HPGDERCC5FEN1HTTALDH1A1 | |
| SCHEMBL1278501 | 0.82 | HPGD (0.43) | HPGDERCC5FEN1HTTALDH1A1 | |
| SCHEMBL1278673 | 0.82 | HPGD (0.43) | HPGDERCC5FEN1HTTALDH1A1 | |
| SCHEMBL5096830 | 0.81 | HPGD (0.46) | HPGDERCC5FEN1NPC1RAB9A | |
| SCHEMBL7949878 | 0.78 | HPGD (0.47) | HPGDERCC5FEN1HTTALDH1A1 | |
| SCHEMBL8955453 | 0.77 | PTPN1 (0.48) | HPGDERCC5FEN1ALDH1A1ALOX12 | |
| SCHEMBL19278858 | 0.77 | HPGD (0.46) | HPGDERCC5FEN1HTTALDH1A1 | |
| SCHEMBL8914360 | 0.77 | HPGD (0.46) | HPGDERCC5FEN1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117326923-A | Fluorine-containing dihydronaphthalenone derivative and preparation method and application thereof | 上海应用技术大学 | 2024-01-02 | — | — | CN | disclosed |