Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137740 | 0.90 | ATM (0.46) | TDP1ATMSMN1; SMN2AKR1C3AKR1C2 | |
| SCHEMBL24346256 | 0.90 | TDP1 (0.46) | TDP1ATMSMN1; SMN2AKR1C3AKR1C2 | |
| SCHEMBL29137726 | 0.90 | ATM (0.41) | TDP1ATMSMN1; SMN2AKR1C3AKR1C2 | |
| SCHEMBL29137724 | 0.90 | ATM (0.41) | TDP1ATMSMN1; SMN2AKR1C3AKR1C2 | |
| SCHEMBL14434051 | 0.82 | ATM (0.58) | TDP1ATMSMN1; SMN2AKR1C3AKR1C2 | |
| SCHEMBL26352680 | 0.80 | ATM (0.55) | TDP1ATMSMN1; SMN2AKR1C3AKR1C2 | |
| SCHEMBL15386362 | 0.80 | ATM (0.55) | TDP1ATMSMN1; SMN2AKR1C3AKR1C2 | |
| SCHEMBL18121906 | 0.80 | ATM (0.55) | TDP1ATMSMN1; SMN2AKR1C3AKR1C2 | |
| SCHEMBL12190659 | 0.79 | ATM (0.47) | TDP1ATMSMN1; SMN2AKR1C3AKR1C2 | |
| SCHEMBL5948033 | 0.79 | AKR1C3 (0.59) | TDP1ATMAKR1C3AKR1C2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384153-A | Methyltransferase inhibitors and uses thereof | 上海赛岚生物科技有限公司 | 2024-01-12 | — | — | CN | disclosed |