Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | AR | P10275 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | AADAC | P22760 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137724 | 1.00 | ATM (0.41) | ATMTDP1APPSMN1; SMN2AR | |
| SCHEMBL29137738 | 0.90 | TDP1 (0.47) | ATMTDP1SMN1; SMN2ARCYP3A4 | |
| SCHEMBL24346256 | 0.83 | TDP1 (0.46) | ATMTDP1SMN1; SMN2ARCYP3A4 | |
| SCHEMBL29137740 | 0.83 | ATM (0.46) | ATMTDP1SMN1; SMN2ARCYP3A4 | |
| SCHEMBL10776718 | 0.82 | APP (0.56) | ATMTDP1APPSMN1; SMN2AR | |
| SCHEMBL2437569 | 0.81 | TDP1 (0.44) | ATMTDP1APPSMN1; SMN2AR | |
| SCHEMBL29137734 | 0.79 | APP (0.41) | APPALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL29137736 | 0.79 | APP (0.41) | APPALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL14434051 | 0.76 | ATM (0.58) | ATMTDP1SMN1; SMN2ARCYP3A4 | |
| SCHEMBL20703719 | 0.75 | MAPT (0.41) | ATMTDP1APPSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117384153-A | Methyltransferase inhibitors and uses thereof | 上海赛岚生物科技有限公司 | 2024-01-12 | — | — | CN | disclosed |