Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137930 | 0.80 | BACE1 (0.31) | — | |
| SCHEMBL29137954 | 0.79 | SCN9A (0.35) | — | |
| SCHEMBL29137957 | 0.79 | ERN1 (0.36) | — | |
| SCHEMBL29137986 | 0.78 | — | — | |
| SCHEMBL29137925 | 0.74 | MAPT (0.44) | GRM5 | |
| SCHEMBL29137963 | 0.71 | CYP4F2 (0.33) | CYP4F2CYP4A11 | |
| SCHEMBL29874548 | 0.68 | GRM2 (0.35) | CYP4F2CYP4A11GRM2 | |
| SCHEMBL20516709 | 0.66 | MAP4K1 (0.61) | — | |
| SCHEMBL4073461 | 0.66 | PLAU (0.46) | — | |
| SCHEMBL30636265 | 0.66 | PLAU (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117062804-A | 1, 3-substituted cyclobutyl derivatives and their use | 诺华股份有限公司 | 2023-11-14 | — | — | CN | disclosed |