Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30688631 | 1.00 | ENPP2 (0.50) | ENPP2MGLLFFAR1LTB4RLTB4R2 | |
| SCHEMBL10269886 | 0.81 | CA1 (0.53) | ENPP2MGLLFFAR1LTB4RLTB4R2 | |
| SCHEMBL2559833 | 0.80 | ENPP2 (0.52) | ENPP2MGLLCA4CA6CA5A | |
| SCHEMBL17319365 | 0.78 | SLC6A4 (0.49) | FFAR1ADRA2AADRA2BADRA2CMAOA | |
| SCHEMBL4363303 | 0.76 | FFAR1 (0.56) | FFAR1LTB4RLTB4R2ALOX5ADRA2A | |
| SCHEMBL31430960 | 0.75 | ENPP2 (0.50) | ENPP2MGLLCA4CA6CA5A | |
| SCHEMBL129343 | 0.75 | ENPP2 (0.50) | ENPP2MGLLCA4CA6CA5A | |
| SCHEMBL30688646 | 0.75 | IDO1 (0.49) | FFAR1LTB4RLTB4R2ALOX5PTGS1 | |
| SCHEMBL22290422 | 0.75 | IDO1 (0.49) | FFAR1LTB4RLTB4R2ALOX5PTGS1 | |
| SCHEMBL17319353 | 0.75 | SLC6A4 (0.49) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343081-A | MAT2A inhibitor, pharmaceutical composition and application thereof | 南京正大天晴制药有限公司 | 2024-01-05 | — | — | CN | disclosed |