Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.48 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20605147 | 0.93 | CNR2 (0.62) | KMT2AKDM4ECNR2L3MBTL1TAS1R3 | |
| SCHEMBL13146407 | 0.83 | MAPK14 (0.56) | KMT2AMEN1CNR2MAPK14NPC1 | |
| SCHEMBL9900222 | 0.82 | TAS1R3 (0.58) | KMT2AMEN1MAPK14L3MBTL1TAS1R3 | |
| SCHEMBL14568525 | 0.81 | MEN1 (0.54) | KMT2AMEN1MAPTKDM4EPOLB | |
| SCHEMBL178563 | 0.81 | MEN1 (0.68) | KMT2AMEN1MAPTKDM4EPOLB | |
| SCHEMBL2085543 | 0.80 | KMT2A (0.56) | KMT2AMEN1MAPTKDM4EPOLB | |
| SCHEMBL26132189 | 0.79 | HDAC8 (0.46) | KMT2AMEN1MAPTKDM4EPOLB | |
| SCHEMBL13544722 | 0.79 | SMYD3 (0.52) | KMT2AMEN1MAPTKDM4EPOLB | |
| SCHEMBL2946787 | 0.78 | KMT2A (0.54) | KMT2AMEN1MAPTKDM4EPOLB | |
| SCHEMBL5630057 | 0.78 | KMT2A (0.54) | KMT2AMEN1MAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117343081-A | MAT2A inhibitor, pharmaceutical composition and application thereof | 南京正大天晴制药有限公司 | 2024-01-05 | — | — | CN | disclosed |