SCHEMBL29138069

SCHEMBL29138069

COO[C@@H]1[C@@H](O)[C@@H](CO)O[C@H]1n1cnc2c(=O)[nH]c(NC(=O)C(C)C)nc21

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.57
TAS1R3 Q7RTX0 1/20 0.53
TAS1R1 Q7RTX1 1/20 0.53
HPGD P15428 2/20 0.51
PAX8 Q06710 1/20 0.44
IMPDH2 P12268 1/20 0.43
IMPDH1 P20839 1/20 0.43
ADORA2A P29274 4/20 0.43
ADORA2B P29275 3/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
ADORA1 P30542 1/20 0.42
HINT1 P49773 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1582579 0.93 KDM4E (0.58) KDM4ETAS1R3TAS1R1HPGDPAX8
SCHEMBL1582583 0.93 KDM4E (0.58) KDM4ETAS1R3TAS1R1HPGDPAX8
SCHEMBL3315671 0.93 KDM4E (0.58) KDM4ETAS1R3TAS1R1HPGDPAX8
SCHEMBL26553755 0.93 KDM4E (0.58) KDM4ETAS1R3TAS1R1HPGDPAX8
SCHEMBL31490988 0.91 TAS1R3 (0.64) KDM4ETAS1R3TAS1R1HPGDPAX8
SCHEMBL7068737 0.90 KDM4E (0.57) KDM4ETAS1R3TAS1R1HPGDPAX8
SCHEMBL7068744 0.90 KDM4E (0.57) KDM4ETAS1R3TAS1R1HPGDPAX8
SCHEMBL19407592 0.90 KDM4E (0.57) KDM4ETAS1R3TAS1R1HPGDPAX8
SCHEMBL7068750 0.90 KDM4E (0.56) KDM4ETAS1R3TAS1R1HPGDPAX8
SCHEMBL25764810 0.90 KDM4E (0.57) KDM4ETAS1R3TAS1R1HPGDPAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117343111-B Preparation method of nucleoside modifier N2-isobutyryl-2' -methoxy guanosine 康羽生命科学技术(苏州)有限公司 2024-02-06 CN claimed
CN-117343111-A Preparation method of nucleoside modifier N2-isobutyryl-2' -methoxy guanosine 康羽生命科学技术(苏州)有限公司 2024-01-05 CN claimed
CN-117343111-B Preparation method of nucleoside modifier N2-isobutyryl-2' -methoxy guanosine 康羽生命科学技术(苏州)有限公司 2024-02-06 CN disclosed
CN-117343111-B Preparation method of nucleoside modifier N2-isobutyryl-2' -methoxy guanosine 康羽生命科学技术(苏州)有限公司 2024-02-06 CN disclosed
CN-117343111-B Preparation method of nucleoside modifier N2-isobutyryl-2' -methoxy guanosine 康羽生命科学技术(苏州)有限公司 2024-02-06 CN disclosed
CN-117343111-A Preparation method of nucleoside modifier N2-isobutyryl-2' -methoxy guanosine 康羽生命科学技术(苏州)有限公司 2024-01-05 CN disclosed
CN-117343111-A Preparation method of nucleoside modifier N2-isobutyryl-2' -methoxy guanosine 康羽生命科学技术(苏州)有限公司 2024-01-05 CN disclosed
CN-117343111-A Preparation method of nucleoside modifier N2-isobutyryl-2' -methoxy guanosine 康羽生命科学技术(苏州)有限公司 2024-01-05 CN disclosed