Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485070 | 0.85 | CA12 (0.53) | TYK2ALDH1A1LMNATRPM4ABL1 | |
| SCHEMBL11782277 | 0.83 | TYK2 (0.46) | TYK2ALDH1A1LMNATRPM4ABL1 | |
| SCHEMBL10562280 | 0.81 | CA12 (0.59) | TYK2ALDH1A1LMNAGAAMAPT | |
| SCHEMBL1397518 | 0.80 | TSHR (0.51) | TYK2ALDH1A1GAAMAPTFABP3 | |
| SCHEMBL9755623 | 0.78 | ALDH1A1 (0.48) | ALDH1A1LMNAGAAPBRM1POLB | |
| Hydrochloric Acid SCHEMBL4372223 | 0.78 | TSHR (0.50) | TYK2ALDH1A1GAAMAPTFABP3 | |
| SCHEMBL27339498 | 0.78 | CA12 (0.55) | ALDH1A1LMNAMAPTCYP3A4 | |
| SCHEMBL30676249 | 0.78 | FABP3 (0.55) | TYK2ALDH1A1TRPM4FABP3FABP4 | |
| SCHEMBL13100052 | 0.78 | ALDH1A1 (0.52) | TYK2ALDH1A1TRPM4FABP3FABP4 | |
| SCHEMBL476833 | 0.78 | ALDH1A1 (0.71) | TYK2ALDH1A1LMNATRPM4FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118440087-A | Preparation and application of antitumor urea narcotine derivative | 华东理工大学 | 2024-08-06 | — | — | CN | disclosed |
| CN-117164598-A | Trifluoromethyl narcotine derivative and preparation method and application thereof | 华东理工大学 | 2023-12-05 | — | — | CN | disclosed |