Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.54 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | ESRRG | P62508 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29138334 | 0.98 | EGFR (0.53) | EGFRERBB2BDKRB2CNR2ALDH1A1 | |
| SCHEMBL1963626 | 0.98 | EGFR (0.53) | EGFRERBB2BDKRB2CNR2ALDH1A1 | |
| SCHEMBL29138335 | 0.98 | EGFR (0.53) | EGFRERBB2BDKRB2CNR2ALDH1A1 | |
| SCHEMBL29138331 | 0.98 | EGFR (0.53) | EGFRERBB2BDKRB2CNR2ALDH1A1 | |
| SCHEMBL29138374 | 0.98 | EGFR (0.53) | EGFRERBB2BDKRB2CNR2ALDH1A1 | |
| SCHEMBL29138333 | 0.98 | EGFR (0.53) | EGFRERBB2BDKRB2CNR2ALDH1A1 | |
| SCHEMBL1827424 | 0.94 | EGFR (0.59) | EGFRERBB2BDKRB2CNR2ALDH1A1 | |
| SCHEMBL16937421 | 0.92 | RAB9A (0.53) | EGFRERBB2CNR2ALDH1A1HPGD | |
| SCHEMBL1962996 | 0.92 | RAB9A (0.53) | EGFRERBB2CNR2ALDH1A1HPGD | |
| SCHEMBL5281386 | 0.88 | HPGD (0.56) | EGFRERBB2CNR2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164469-A | Preparation method of milone derivative | 杭华油墨股份有限公司 | 2023-12-05 | — | — | CN | disclosed |