SCHEMBL29138520

SCHEMBL29138520

CCOC(=O)C=Cc1c(C)noc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
MLYCD O95822 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
HCAR2 Q8TDS4 1/20 0.43
CACNA1F O60840 2/20 0.42
CACNA1D Q01668 2/20 0.42
CACNA1S Q13698 2/20 0.42
CACNA1C Q13936 2/20 0.42
TTR P02766 1/20 0.42
DPP4 P27487 1/20 0.42
CNKSR1 Q969H4 1/20 0.41
CYP3A4 P08684 1/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
ALDH1A1 P00352 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1124489 0.77 GAA (0.49) L3MBTL1HCAR2KDM4EMAPTALDH1A1
SCHEMBL1124487 0.77 GAA (0.49) L3MBTL1HCAR2KDM4EMAPTALDH1A1
SCHEMBL29611878 0.75 LMNA (0.35) L3MBTL1CACNA1FCACNA1DCACNA1SCACNA1C
SCHEMBL13304571 0.75 CNKSR1 (0.48) CA12CA1CA2CA7CA9
SCHEMBL31124634 0.74 POLB (0.48) CA12CA1CA2CA7CA9
Hydrochloric Acid SCHEMBL9837034 0.73 CA12 (0.49) CA12CA1CA2CA7CA9
SCHEMBL18272368 0.73 CA12 (0.51) CA12CA1CA2CA7CA9
SCHEMBL18260220 0.73 CA12 (0.51) CA12CA1CA2CA7CA9
SCHEMBL18678032 0.72 CA12 (0.44) CA12CA1CA2CA7CA9
SCHEMBL2691468 0.72 CA12 (0.50) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117069720-A 5-HT 2A Receptor agonist, preparation method and application thereof 上海翊石医药科技有限公司 2023-11-17 CN disclosed