SCHEMBL29138532

SCHEMBL29138532

O=CCC1COc2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PPARG P37231 5/20 0.42
PPARD Q03181 5/20 0.42
PSMB5 P28074 4/20 0.41
MAOB P27338 2/20 0.41
LTB4R Q15722 1/20 0.41
LTB4R2 Q9NPC1 1/20 0.41
FFAR1 O14842 2/20 0.39
PPARA Q07869 1/20 0.39
DRD2 P14416 1/20 0.38
DRD3 P35462 1/20 0.38
HTR2C P28335 1/20 0.38
KCNH2 Q12809 1/20 0.38
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
CYP19A1 P11511 1/20 0.36
PSMB8 P28062 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5175312 0.83 KCNH2 (0.39) LTB4RLTB4R2KCNH2
SCHEMBL204961 0.79 PPARG (0.62) PPARGPPARDPSMB5FFAR1PPARA
SCHEMBL203850 0.79 PPARG (0.62) PPARGPPARDPSMB5FFAR1PPARA
SCHEMBL13348213 0.77 PPARG (0.39) PPARGPPARDFFAR1PPARAHTR2C
SCHEMBL2316931 0.76 LTB4R (0.47) PPARGPPARDPSMB5MAOBLTB4R
SCHEMBL6099078 0.76 LTB4R (0.47) PPARGPPARDPSMB5MAOBLTB4R
SCHEMBL506552 0.76 CYP2D6 (0.47) PPARGPPARDPSMB5MAOBLTB4R
SCHEMBL19574896 0.76 LTB4R (0.44) PSMB5MAOBLTB4RLTB4R2DRD2
SCHEMBL2688677 0.76 LTB4R (0.44) PSMB5MAOBLTB4RLTB4R2DRD2
SCHEMBL2316932 0.76 LTB4R (0.47) PPARGPPARDPSMB5MAOBLTB4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117069720-A 5-HT 2A Receptor agonist, preparation method and application thereof 上海翊石医药科技有限公司 2023-11-17 CN disclosed