Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.51 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.51 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17755042 | 0.84 | CTSD (0.53) | MAPTLMNACTSDGAATSHR | |
| SCHEMBL29138542 | 0.84 | MAPT (0.50) | MAPTLMNAKMT2AMEN1PLIN1 | |
| SCHEMBL14372527 | 0.82 | TSHR (0.54) | MAPTLMNAKMT2AMEN1PLIN1 | |
| SCHEMBL29138521 | 0.82 | MAPT (0.46) | MAPTLMNAKMT2AMEN1PLIN1 | |
| SCHEMBL11254735 | 0.81 | MAPT (0.50) | MAPTKMT2AMEN1POLBGAA | |
| SCHEMBL11254743 | 0.81 | MAPT (0.50) | MAPTKMT2AMEN1POLBGAA | |
| SCHEMBL21457686 | 0.80 | NPC1 (0.49) | MAPTLMNAKMT2AMEN1PLIN1 | |
| SCHEMBL4146557 | 0.80 | TSHR (0.47) | MAPTLMNAKMT2AMEN1POLB | |
| SCHEMBL9510890 | 0.80 | TSHR (0.47) | MAPTLMNAKMT2AMEN1POLB | |
| SCHEMBL17169101 | 0.80 | KDM4E (0.49) | MAPTLMNAKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069720-A | 5-HT 2A Receptor agonist, preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-11-17 | — | — | CN | disclosed |