Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14677142 | 0.89 | LMNA (0.43) | LMNAMEN1KMT2AGAACRHBP | |
| SCHEMBL2616802 | 0.80 | LMNA (0.43) | LMNAMEN1KMT2AGAACRHBP | |
| SCHEMBL96071 | 0.79 | — | — | |
| SCHEMBL14759391 | 0.78 | LMNA (0.42) | LMNAMEN1KMT2AGAACRHBP | |
| SCHEMBL18647926 | 0.78 | TLR8 (0.42) | LMNAGAACRHBPCRHR2ALDH1A1 | |
| SCHEMBL2238495 | 0.77 | LMNA (0.48) | LMNAMEN1KMT2AGAACRHBP | |
| SCHEMBL8237746 | 0.77 | LMNA (0.44) | LMNAMEN1KMT2AGAACRHBP | |
| SCHEMBL3690521 | 0.77 | LMNA (0.41) | LMNAMEN1KMT2AGAACRHBP | |
| SCHEMBL22459185 | 0.77 | TLR8 (0.41) | LMNAKMT2AGAACRHBPCRHR2 | |
| SCHEMBL18898429 | 0.77 | TLR8 (0.41) | LMNAKMT2AGAACRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069720-A | 5-HT 2A Receptor agonist, preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-11-17 | — | — | CN | disclosed |