SCHEMBL29138565

SCHEMBL29138565

COc1ccccc1C(F)(F)CCO

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.42
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA12 O43570 1/20 0.41
CA4 P22748 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39
NR3C2 P08235 2/20 0.39
NR3C1 P04150 3/20 0.39
MAOB P27338 1/20 0.38
GAA P10253 1/20 0.38
LMNA P02545 2/20 0.38
AGTR1 P30556 1/20 0.38
CYP1A2 P05177 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ENPP2 Q13822 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9282381 0.85 CA1 (0.44) ATMCA1CA2CA12CA4
SCHEMBL29138553 0.80 CA1 (0.43) ATMCA1CA2CA12CA4
SCHEMBL23886282 0.78 CA1 (0.44) ATMCA1CA2CA12CA4
SCHEMBL21556811 0.78 CA1 (0.44) ATMCA1CA2CA12CA4
SCHEMBL29138515 0.77 PTGDR2 (0.39) TSHRNR3C1GAALMNAMEN1
SCHEMBL30669694 0.77 PTGDR2 (0.39) TSHRNR3C1GAALMNAMEN1
Hydrochloric Acid SCHEMBL29681943 0.76 CA1 (0.43) ATMCA1CA2CA12CA4
Hydrochloric Acid SCHEMBL9275355 0.76 CA1 (0.43) ATMCA1CA2CA12CA4
SCHEMBL30039006 0.76 SMN1; SMN2 (0.49) ATMCA1CA2CA12CA7
SCHEMBL9886692 0.75 ATM (0.42) ATMCA1CA2CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117069720-A 5-HT 2A Receptor agonist, preparation method and application thereof 上海翊石医药科技有限公司 2023-11-17 CN disclosed