SCHEMBL29138515

SCHEMBL29138515

COc1ccc(Br)cc1C(F)(F)CCO

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.39
KDM4E B2RXH2 4/20 0.38
TDP1 Q9NUW8 2/20 0.38
MEN1 O00255 2/20 0.38
ALDH1A1 P00352 2/20 0.38
KMT2A Q03164 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
USP2 O75604 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
THRB P10828 1/20 0.38
ALOX15 P16050 1/20 0.38
CASP1 P29466 1/20 0.38
HTT P42858 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
HSD17B10 Q99714 1/20 0.38
S1PR1 P21453 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30669694 1.00 PTGDR2 (0.39) PTGDR2KDM4ETDP1MEN1ALDH1A1
SCHEMBL2273425 0.78 S1PR4 (0.44) PTGDR2KDM4ETDP1ALDH1A1L3MBTL1
SCHEMBL29427047 0.78 S1PR4 (0.44) PTGDR2KDM4ETDP1ALDH1A1L3MBTL1
SCHEMBL29138565 0.77 ATM (0.42) MEN1ALDH1A1KMT2AGAAHSD17B10
SCHEMBL11371205 0.76 PTGDR2 (0.45) PTGDR2KDM4ETDP1MEN1ALDH1A1
SCHEMBL29060113 0.73 ALDH1A1 (0.38) PTGDR2KDM4ETDP1MEN1ALDH1A1
SCHEMBL29060290 0.73 PTGDR2 (0.43) PTGDR2KDM4EMEN1ALDH1A1KMT2A
SCHEMBL4820133 0.73 PTGDR2 (0.45) PTGDR2KDM4ETDP1MEN1ALDH1A1
SCHEMBL3531969 0.73 NR3C1 (0.55) NR3C1
SCHEMBL1542948 0.72 PTGDR2 (0.56) PTGDR2KDM4ETDP1ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117069720-A 5-HT 2A Receptor agonist, preparation method and application thereof 上海翊石医药科技有限公司 2023-11-17 CN disclosed