Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29120327 | 0.96 | ALDH1A1 (0.43) | ALDH1A1PKMKMT2APOLBRAB9A | |
| SCHEMBL745826 | 0.82 | ALDH1A1 (0.46) | ALDH1A1PKMKMT2APOLBRAB9A | |
| Hydrogen Sulfide SCHEMBL17534845 | 0.81 | ALDH1A1 (0.45) | ALDH1A1PKMKMT2APOLBRAB9A | |
| SCHEMBL29139343 | 0.80 | ALDH1A1 (0.37) | ALDH1A1PKMKMT2APOLBHDAC1 | |
| SCHEMBL23235914 | 0.78 | ALDH1A1 (0.37) | ALDH1A1KMT2APOLBHDAC1HDAC2 | |
| SCHEMBL44725 | 0.77 | ALDH1A1 (0.50) | ALDH1A1PKMKMT2APOLBHDAC1 | |
| SCHEMBL23859811 | 0.76 | ALDH1A1 (0.36) | ALDH1A1KMT2APOLBHDAC1HDAC2 | |
| SCHEMBL23235910 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KMT2APOLBHDAC1HDAC2 | |
| SCHEMBL616908 | 0.75 | ALDH1A1 (0.54) | ALDH1A1PKMKMT2APOLBRAB9A | |
| SCHEMBL10340551 | 0.75 | ALDH1A1 (0.43) | ALDH1A1PKMKMT2APOLBHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117412741-A | Maytansine-antibody conjugates and methods of use thereof | 安吉克公司 | 2024-01-16 | — | — | CN | claimed |
| CN-117412741-A | Maytansine-antibody conjugates and methods of use thereof | 安吉克公司 | 2024-01-16 | — | — | CN | disclosed |