Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELE | P16581 | 1/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439142 | 0.79 | SELE (0.56) | SELEVCAM1HDAC3HDAC1HDAC6 | |
| SCHEMBL30408264 | 0.79 | SELE (0.56) | SELEVCAM1HDAC3HDAC1HDAC6 | |
| SCHEMBL7254304 | 0.71 | SELE (0.40) | SELEVCAM1HDAC3HDAC1HDAC6 | |
| SCHEMBL6484704 | 0.69 | SELE (0.56) | SELEVCAM1HDAC3HDAC1HDAC6 | |
| SCHEMBL30408920 | 0.69 | SELE (0.56) | SELEVCAM1HDAC3HDAC1HDAC6 | |
| SCHEMBL654782 | 0.69 | SELE (0.56) | SELEVCAM1HDAC3HDAC1HDAC6 | |
| SCHEMBL1368716 | 0.69 | SELE (0.61) | SELEVCAM1HDAC3HDAC1HDAC6 | |
| SCHEMBL1604838 | 0.66 | SELE (0.69) | SELEVCAM1HDAC3HDAC1HDAC6 | |
| SCHEMBL29737503 | 0.66 | SELE (0.64) | SELEVCAM1MEN1 | |
| SCHEMBL16031220 | 0.66 | SELE (0.64) | SELEVCAM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111601807-B | Exo-azaspiro inhibitors of MENIN-MLL interactions | 詹森药业有限公司 | 2023-03-31 | — | — | CN | disclosed |