Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30768235 | 0.91 | PRSS1 (0.44) | PRSS1PRSS2PRSS3ALDH1A1TSHR | |
| SCHEMBL28479311 | 0.86 | PRSS1 (0.45) | PRSS1PRSS2PRSS3ALDH1A1TSHR | |
| SCHEMBL29139948 | 0.85 | PRSS1 (0.52) | PRSS1PRSS2PRSS3ALDH1A1TSHR | |
| SCHEMBL28532492 | 0.85 | PRSS1 (0.52) | PRSS1PRSS2PRSS3ALDH1A1TSHR | |
| SCHEMBL6479756 | 0.84 | PRSS1 (0.50) | PRSS1PRSS2PRSS3ALDH1A1TSHR | |
| SCHEMBL29148911 | 0.84 | PRSS1 (0.50) | PRSS1PRSS2PRSS3ALDH1A1TSHR | |
| SCHEMBL671032 | 0.81 | ALDH1A1 (0.55) | PRSS1PRSS2PRSS3ALDH1A1TSHR | |
| SCHEMBL1586807 | 0.81 | PRSS1 (0.53) | PRSS1PRSS2PRSS3ALDH1A1TSHR | |
| SCHEMBL30479012 | 0.80 | CYP3A4 (0.51) | PRSS1PRSS2PRSS3ALDH1A1TSHR | |
| SCHEMBL27199692 | 0.80 | CYP3A4 (0.51) | PRSS1PRSS2PRSS3ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117683029-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-117430601-A | Bcl-2 inhibitors | 百济神州有限公司 | 2024-01-23 | — | — | CN | disclosed |
| CN-112437772-B | Bcl-2 inhibitors | 百济神州有限公司 | 2023-11-21 | — | — | CN | disclosed |