Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1913728 | 1.00 | LMNA (0.51) | LMNASMN1; SMN2POLBHTTCACNA2D1 | |
| SCHEMBL3118348 | 1.00 | LMNA (0.51) | LMNASMN1; SMN2POLBHTTCACNA2D1 | |
| SCHEMBL3112068 | 0.88 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2POLBCACNA2D1ADRA1A | |
| SCHEMBL1913866 | 0.88 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2POLBCACNA2D1ADRA1A | |
| SCHEMBL3241280 | 0.88 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2POLBCACNA2D1ADRA1A | |
| SCHEMBL3119985 | 0.87 | KDM4E (0.45) | HTTCACNA2D1ADRA1ACACNB3CACNA1C | |
| SCHEMBL1913968 | 0.87 | CACNA2D1 (0.42) | SMN1; SMN2POLBHTTCACNA2D1ADRA1A | |
| SCHEMBL6453186 | 0.87 | KDM4E (0.45) | HTTCACNA2D1ADRA1ACACNB3CACNA1C | |
| SCHEMBL1913765 | 0.87 | KDM4E (0.45) | HTTCACNA2D1ADRA1ACACNB3CACNA1C | |
| SCHEMBL7116294 | 0.87 | CACNA2D1 (0.42) | SMN1; SMN2POLBHTTCACNA2D1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117045653-A | Diseases and treatments associated with toxic aldehydes | 奥尔德拉医疗公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-111135171-B | Diseases and treatments associated with toxic aldehydes | 奥尔德拉医疗公司 | 2023-09-08 | — | — | CN | disclosed |